- idUS
- Listar por autor
Listar por autor "Checa Rodríguez, Cintia"
Mostrando ítems 1-7 de 7
-
Trabajo Fin de Grado
Células madre y su aplicación en medicina reproductiva.
Hernández Moreno, Belén (2023-05-31)La infertilidad es un problema que afecta a una fracción importante de la población. Existen numerosos métodos para ...
-
Artículo
CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells
Gómez Cabello, Daniel; Checa Rodríguez, Cintia; Abad, María; Serrano, Manuel; Huertas Sánchez, Pablo (Elsevier, 2017)Acquired genomic instability is one of the major concerns for the clinical use of induced pluripotent stem cells (iPSCs). ...
-
Artículo
DNA end resection requires constitutive sumoylation of CtIP by CBX4
Soria Bretones, Isabel; Cepeda García, Cristina; Checa Rodríguez, Cintia; Heyer, Vincent; Reina San Martín, Bernardo; Soutoglou, Evi; Huertas Sánchez, Pablo (Nature Publishing Group, 2017)DNA breaks are complex DNA lesions that can be repaired by two alternative mechanisms: non-homologous end-joining and ...
-
Artículo
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
Alonso de la Vega, Ignacio; Paz Cabrera, María Cristina; Rother, Magdalena B; Wiegant, Wouter W; Checa Rodríguez, Cintia; Hernández Fernaud, Juan Ramón; Huertas Sánchez, Pablo; Freire, Raimundo; Attikum, Haico van; Smits, Veronique A J (Oxford University Press, 2020)Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the ...
-
Tesis Doctoral
Regulation of DNA end resection by cell stemness
Checa Rodríguez, Cintia (2020-01-20)The ability to reprogram somatic cells into induced pluripotent stem cells (iPSCs) holds great potential for clinic ...
-
Artículo
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer
Rabinowicz, Noa; Mangala, Lingegowda S.; Brown, Kevin R.; Checa Rodríguez, Cintia; Castiel, Asher; Huertas Sánchez, Pablo (Impact Journals, 2017)Advanced ovarian cancer is an incurable disease. Thus, novel therapies are required. We wished to identify new therapeutic ...
-
Artículo
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
Jachimowicz, Ron D.; Beleggia, Filippo; Isensee, Jörg; Velpula, Bhagya Bhavana; Goergens, Jonas; Bustos, Matias A.; Checa Rodríguez, Cintia; Huertas Sánchez, Pablo (Elsevier, 2020)Genomic instability can be a hallmark of both human genetic disease and cancer. We identify a deleterious UBQLN4 mutation ...